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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LTK
All Species:
3.03
Human Site:
S464
Identified Species:
6.67
UniProt:
P29376
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29376
NP_002335.2
864
91681
S464
L
Q
E
M
R
L
P
S
P
E
L
E
L
S
K
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
T429
T
H
K
P
E
E
D
T
F
G
V
S
I
A
V
Rhesus Macaque
Macaca mulatta
XP_001099288
876
93443
L493
D
N
V
T
C
M
D
L
P
N
P
P
G
P
L
Dog
Lupus familis
XP_540136
1905
205583
Q1359
H
Q
E
L
Q
A
M
Q
M
E
L
Q
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P08923
888
94418
G460
L
W
G
T
R
L
P
G
P
E
L
E
L
S
K
Rat
Rattus norvegicus
NP_001101233
577
63040
F206
R
A
L
G
H
G
A
F
G
E
V
Y
E
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421140
1389
151159
R814
K
Q
Q
L
E
G
A
R
A
R
L
Q
S
P
E
Frog
Xenopus laevis
O73798
1358
153845
S949
F
L
L
V
G
I
I
S
I
V
C
F
V
F
K
Zebra Danio
Brachydanio rerio
NP_001006661
1530
165453
R889
K
N
H
L
H
A
V
R
I
R
L
Q
S
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652600
1701
185560
Q1147
R
H
K
M
L
V
E
Q
D
L
Q
L
T
R
L
Honey Bee
Apis mellifera
XP_392254
1436
158335
R840
R
K
A
L
I
Q
R
R
Q
V
M
F
G
N
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.2
71.8
28.2
N.A.
77.2
52.7
N.A.
N.A.
40.6
21.3
36
N.A.
23.2
26.4
N.A.
N.A.
Protein Similarity:
100
37.9
74.1
34.7
N.A.
83.1
55.6
N.A.
N.A.
48.2
34.6
43.6
N.A.
32.3
37.6
N.A.
N.A.
P-Site Identity:
100
0
6.6
26.6
N.A.
73.3
6.6
N.A.
N.A.
13.3
13.3
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
33.3
13.3
53.3
N.A.
73.3
13.3
N.A.
N.A.
40
33.3
26.6
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
19
19
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
19
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
19
0
19
10
10
0
0
37
0
19
10
0
28
% E
% Phe:
10
0
0
0
0
0
0
10
10
0
0
19
0
10
0
% F
% Gly:
0
0
10
10
10
19
0
10
10
10
0
0
19
10
10
% G
% His:
10
19
10
0
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
10
0
19
0
0
0
10
0
0
% I
% Lys:
19
10
19
0
0
0
0
0
0
0
0
0
0
0
28
% K
% Leu:
19
10
19
37
10
19
0
10
0
10
46
10
19
0
28
% L
% Met:
0
0
0
19
0
10
10
0
10
0
10
0
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
0
0
0
10
0
0
19
0
28
0
10
10
0
37
0
% P
% Gln:
0
28
10
0
10
10
0
19
10
0
10
28
0
0
0
% Q
% Arg:
28
0
0
0
19
0
10
28
0
19
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
19
0
0
0
10
28
19
0
% S
% Thr:
10
0
0
19
0
0
0
10
0
0
0
0
10
0
0
% T
% Val:
0
0
10
10
0
10
10
0
0
19
19
0
10
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _